{"id":89917,"date":"2026-08-13T10:00:00","date_gmt":"2026-08-13T15:00:00","guid":{"rendered":"https:\/\/www.rxbriefcase.com\/?post_type=rxbriefly&p=89917"},"modified":"2026-08-13T10:00:00","modified_gmt":"2026-08-13T15:00:00","slug":"%f0%9f%92%8a-ditching-the-vaccine-fridge","status":"publish","type":"rxbriefly","link":"https:\/\/www.rxbriefcase.com\/fr\/rxbriefly-item\/%f0%9f%92%8a-ditching-the-vaccine-fridge\/","title":{"rendered":"\ud83d\udc8a Ditching the vaccine fridge?"},"content":{"rendered":"<div>\n<div>\n<div><a href=\"https:\/\/www.rxbriefcase.com\/fr\/rxbriefly\/?utm_source=rxbriefly&amp;utm_medium=newsletter&amp;utm_campaign=ditching-the-vaccine-fridge\" rel=\"noopener\" target=\"_blank\"><img decoding=\"async\" alt=\"\" src=\"https:\/\/media.beehiiv.com\/cdn-cgi\/image\/fit=scale-down,format=auto,onerror=redirect,quality=80\/uploads\/asset\/file\/1b7b97a3-9c4e-4863-9cdd-b2ccac23a5d1\/Asset_13.png?t=1776360019\"><\/a><\/div>\n<p><b>Good morning dispensers of wisdom!<\/b><\/p>\n<p>Remember when getting sheep&#8217;s wool stuck to your sweater was just an annoying laundry mishap? Scientists have officially found a way to make it sound like high-tech medicine. <a href=\"https:\/\/www.sciencedaily.com\/releases\/2026\/08\/260812015210.htm?utm_source=rxbriefly&amp;utm_medium=newsletter&amp;utm_campaign=ditching-the-vaccine-fridge\" target=\"_blank\" rel=\"noopener noreferrer nofollow\">A new study published this week<\/a> found that extracting keratin from raw sheep&#8217;s wool can actually be used as a biological scaffold to help regrow human bone. In animal trials, the wool-derived protein helped broken bones regenerate faster and with a cleaner structure than standard collagen scaffolds. So the next time a patient comes into your pharmacy complaining about itchy wool socks, you can technically inform them they&rsquo;re wearing orthopedic infrastructure. <\/p>\n<p><span>Today&rsquo;s issue takes 5 minutes to read<\/span>. Only got one? Here&rsquo;s what to know:<\/p>\n<ul>\n<li>\n<p>&#129728; Tirzepatide linked to 32% drop in MACE for type 2 diabetes patients<\/p>\n<\/li>\n<li>\n<p>&#9888;&#65039; Shortages for Dilaudid (1 mg, 2 mg) <\/p>\n<\/li>\n<li>\n<p>&#129514; World&#8217;s first fridge-free tetanus shot passes Phase 1 human trial<\/p>\n<\/li>\n<li>\n<p>&#129440; Shigella vaccine posts 89% efficacy in Phase 2 trial<\/p>\n<\/li>\n<li>\n<p>&#127973; LTC rapid testing could prevent 8,000 ER visits annually<\/p>\n<\/li>\n<li>\n<p>&#129516; Gene variants linked to inherited hyperhidrosis offer new treatment target<\/p>\n<\/li>\n<\/ul>\n<p>Let&rsquo;s get into it.<\/p>\n<div>\n<h1><span>Staying #Up2Date <\/span>&#128680;<\/h1>\n<\/div>\n<div>\n<p><b>1: Beyond Weight Loss: Tirzepatide&rsquo;s Heart-Shielding Powers<\/b><\/p>\n<p>A <a href=\"https:\/\/www.bmj.com\/content\/394\/bmj-2026-100011?utm_source=rxbriefly&amp;utm_medium=newsletter&amp;utm_campaign=ditching-the-vaccine-fridge\" target=\"_blank\" rel=\"noopener noreferrer nofollow\">large study in <\/a><i><a href=\"https:\/\/www.bmj.com\/content\/394\/bmj-2026-100011?utm_source=rxbriefly&amp;utm_medium=newsletter&amp;utm_campaign=ditching-the-vaccine-fridge\" target=\"_blank\" rel=\"noopener noreferrer nofollow\">The BMJ<\/a><\/i> looked at over 52,000 adults with type 2 diabetes and existing heart disease to see how tirzepatide holds up against older diabetes meds like sitagliptin. The results were impressive: starting tirzepatide was linked to a <b>32% lower risk of major heart events<\/b> like heart attacks and strokes, with benefits starting to show up in as little as 3 months. Even better, all-cause mortality dropped by 45%. Dual GIP\/GLP-1 meds aren&#8217;t just great for A1c and weight loss, they&rsquo;re proving to be serious powerhouses for long-term heart protection.<\/p>\n<p><span><b>2: The Statin Gate Opens Wider: Millions More Now Qualify <\/b><\/span><\/p>\n<p><span>A JAMA study evaluated <\/span><span><a href=\"https:\/\/www.tctmd.com\/news\/researchers-offer-preview-2026-dyslipidemia-guidelines-impact?utm_source=rxbriefly&amp;utm_medium=newsletter&amp;utm_campaign=ditching-the-vaccine-fridge\" target=\"_blank\" rel=\"noopener noreferrer nofollow\">updated 2026 US cholesterol guidelines<\/a><\/span><span> that shift to using newer, race-free risk calculators to look at 30-year heart health trajectories instead of just short-term risk. The verdict? <\/span><span><b>About 21.5 million more US adults<\/b><\/span><span> now qualify for primary prevention statin therapy, mostly individuals in their 40s and 50s who previously seemed &#8220;low risk.&#8221; The shift reflects a growing focus on managing lifetime exposure to LDL cholesterol early on, rather than waiting until short-term risk climbs later in life.<\/span><\/p>\n<p><b>3: CGM: One Size Doesn&#8217;t Fit All<\/b><\/p>\n<p>A <a href=\"https:\/\/jamanetwork.com\/journals\/jamainternalmedicine\/article-abstract\/2851941?utm_source=rxbriefly&amp;utm_medium=newsletter&amp;utm_campaign=ditching-the-vaccine-fridge\" target=\"_blank\" rel=\"noopener noreferrer nofollow\">review<\/a> of randomized trials and clinical guidelines evaluating continuous glucose monitor (CGM) use beyond type 1 diabetes found that CGM use was associated with a modest yet consistent reduction in HbA1c (roughly 0.3%) when compared to finger-stick monitoring in adults with type 2 diabetes. These findings show that CGM should be deployed in response to a specific patient problem rather than default intervention in those with type 2 diabetes.&nbsp;<\/p>\n<\/div>\n<div>\n<h1><span>Shelf Watch <\/span>&#127973;<\/h1>\n<\/div>\n<div>\n<p><span><b>Drug Shortages<\/b><\/span><span> &#9888;&#65039;<\/span><\/p>\n<p><a href=\"https:\/\/healthproductshortages.ca\/shortage\/291170?utm_source=rxbriefly&amp;utm_medium=newsletter&amp;utm_campaign=ditching-the-vaccine-fridge\" target=\"_blank\" rel=\"noopener noreferrer nofollow\"><b>Dilaudid<\/b><\/a><a href=\"https:\/\/healthproductshortages.ca\/shortage\/291170?utm_source=rxbriefly&amp;utm_medium=newsletter&amp;utm_campaign=ditching-the-vaccine-fridge\" target=\"_blank\" rel=\"noopener noreferrer nofollow\">&nbsp;<\/a><\/p>\n<ul>\n<li>\n<p>Company: Purdue Pharma<\/p>\n<\/li>\n<li>\n<p>Drug class: Opioid analgesics<\/p>\n<\/li>\n<li>\n<p>DIN: 00705438 (1 mg), 00125083 (2 mg)<\/p>\n<\/li>\n<li>\n<p>Strength affected: 1 mg, 2 mg (Tablets)<\/p>\n<\/li>\n<li>\n<p>Shortage status: Actual shortage (2 mg), Anticipated shortage (1 mg)<\/p>\n<\/li>\n<li>\n<p>Reason for shortage: Demand increase for the drug<\/p>\n<\/li>\n<li>\n<p>Start date: 2026-08-10<\/p>\n<\/li>\n<li>\n<p>Estimated end date: 2026-08-21 (1 mg), 2026-10-19 (2 mg)<\/p>\n<\/li>\n<\/ul>\n<p><a href=\"https:\/\/healthproductshortages.ca\/shortage\/207103?utm_source=rxbriefly&amp;utm_medium=newsletter&amp;utm_campaign=ditching-the-vaccine-fridge\" target=\"_blank\" rel=\"noopener noreferrer nofollow\"><b>pms-Lithium Carbonate<\/b><\/a><a href=\"https:\/\/healthproductshortages.ca\/shortage\/207103?utm_source=rxbriefly&amp;utm_medium=newsletter&amp;utm_campaign=ditching-the-vaccine-fridge\" target=\"_blank\" rel=\"noopener noreferrer nofollow\">&nbsp;<\/a><\/p>\n<ul>\n<li>\n<p>Company: Pharmascience Inc.<\/p>\n<\/li>\n<li>\n<p>Drug class: Antipsychotics \/ Mood stabilizers<\/p>\n<\/li>\n<li>\n<p>DIN: 02216140<\/p>\n<\/li>\n<li>\n<p>Strength affected: 300 mg (Capsules)<\/p>\n<\/li>\n<li>\n<p>Shortage status: Actual shortage<\/p>\n<\/li>\n<li>\n<p>Reason for shortage: Disruption of the manufacture of the drug<\/p>\n<\/li>\n<li>\n<p>Start date: 2023-10-23<\/p>\n<\/li>\n<li>\n<p>Updated date: <span>2026-08-12<\/span><\/p>\n<\/li>\n<li>\n<p>Estimated end date: Unknown<\/p>\n<\/li>\n<\/ul>\n<\/div>\n<div>\n<h1><span><b>&#128176; Your Two Cents is Worth $25<\/b><\/span><\/h1>\n<\/div>\n<div>\n<div><img decoding=\"async\" alt=\"\" src=\"https:\/\/media.beehiiv.com\/cdn-cgi\/image\/fit=scale-down,format=auto,onerror=redirect,quality=80\/uploads\/asset\/file\/009f37db-a7dd-4642-890c-cef7d31d0c13\/image.jpeg?t=1786547562\"><\/div>\n<p>Have 10 minutes? Power of VAX wants to hear from Canadian pharmacists, <b>with a $25 honorarium for the first 1,000 pharmacists<\/b>&nbsp;<a href=\"https:\/\/www.surveymonkey.ca\/r\/6K72RFD?utm_source=rxbriefly&amp;utm_medium=newsletter&amp;utm_campaign=ditching-the-vaccine-fridge\" target=\"_blank\" rel=\"noopener noreferrer nofollow\">who complete the survey<\/a>.<\/p>\n<p>Power of VAX is a pharmacist-focused program designed to strengthen vaccination practices and improve patient outcomes. Your answers about day-to-day practice will help shape this year&rsquo;s program around what pharmacists actually need.<\/p>\n<p>And it has some solid results behind it. Last year, participating pharmacists saw a <b>3x improvement in vaccination effectiveness<\/b>, and the program earned the <b>FIP Seal<\/b>, a mark of quality and professionalism in pharmacy education from the International Pharmaceutical Federation.<\/p>\n<p><b>The survey closes August 21<\/b> and the honorariums are limited. So if you want in, sooner is better.<\/p>\n<div><a target=\"_blank\" rel=\"noopener nofollow noreferrer\" href=\"https:\/\/www.surveymonkey.ca\/r\/6K72RFD?utm_source=rxbriefly&amp;utm_medium=newsletter&amp;utm_campaign=ditching-the-vaccine-fridge\"><span> Take the Survey <\/span><\/a><\/div>\n<\/div>\n<div>\n<h1><span>Out of the Cold: A Fridge-Free Tetanus Shot? <\/span><\/h1>\n<\/div>\n<div>\n<p><i>Science just made it one step closer to making vaccine fridges obsolete&hellip;<\/i><\/p>\n<p><b>What happened:<\/b> A Phase 1 trial published in <i><a href=\"https:\/\/www.thelancet.com\/journals\/eclinm\/article\/PIIS2589-5370(26)00369-X\/fulltext?utm_source=rxbriefly&amp;utm_medium=newsletter&amp;utm_campaign=ditching-the-vaccine-fridge\" target=\"_blank\" rel=\"noopener noreferrer nofollow\">eClinicalMedicine<\/a><\/i> shows that an experimental, room-temperature-stable tetanus-diphtheria (Td) vaccine is safe and generates an immune response comparable to standard refrigerated boosters. <\/p>\n<p>The new formulation, SPVX02 (developed by UK biotech Stablepharma), takes an existing WHO-prequalified Td vaccine (<i>Tetadif<\/i>) and reformulates it into a dried powder using sugar-based stabilization (trehalose). It gets reconstituted with sterile water right before injection. In 60 healthy adults, 100% achieved protective antitoxin levels against both tetanus and diphtheria by Day 28, matching licensed vaccines. As reported by <a href=\"https:\/\/www.bbc.com\/news\/articles\/ce85qe8j0nzo?utm_source=rxbriefly&amp;utm_medium=newsletter&amp;utm_campaign=ditching-the-vaccine-fridge\" target=\"_blank\" rel=\"noopener noreferrer nofollow\">BBC News<\/a> and <i><a href=\"https:\/\/www.emjreviews.com\/general-healthcare\/news\/successful-trials-of-fridge-free-vaccines-to-boost-global-distribution\/?utm_source=rxbriefly&amp;utm_medium=newsletter&amp;utm_campaign=ditching-the-vaccine-fridge\" target=\"_blank\" rel=\"noopener noreferrer nofollow\">EMJ Reviews<\/a><\/i>, this successful human trial marks a major milestone for thermostable immunization.<\/p>\n<p><span><b>Why it matters:<\/b><\/span><span> Standard Td vaccines use aluminum adjuvants that permanently aggregate and lose potency if they freeze (0&deg;C) or overheat (&gt;8&deg;C).<\/span> SPVX02 fixes both extremes:<\/p>\n<ul>\n<li>\n<p><b>24-Month Room-Temp Storage:<\/b>&nbsp;<span>Retains full potency at 30&deg;C for at least 24 months.<\/span><\/p>\n<\/li>\n<li>\n<p><b>Freeze and Heat Proof:<\/b>&nbsp;<span>Retained full potency through three extreme temperature cycles ranging from -20&deg;C to +40&deg;C.<\/span><\/p>\n<\/li>\n<\/ul>\n<p><span>According to the World Health Organization, cold-chain failures and transport breaches contribute to <\/span><span><a href=\"https:\/\/www.bmj.com\/content\/394\/bmj-2026-100517?utm_source=rxbriefly&amp;utm_medium=newsletter&amp;utm_campaign=ditching-the-vaccine-fridge\" target=\"_blank\" rel=\"noopener noreferrer nofollow\">roughly half of all vaccines wasted globally each year<\/a><\/span><span>.<\/span><\/p>\n<div><img decoding=\"async\" alt=\"\" src=\"https:\/\/media.beehiiv.com\/cdn-cgi\/image\/fit=scale-down,format=auto,onerror=redirect,quality=80\/uploads\/asset\/file\/8431e090-c0af-4a51-97f7-09b3f993658d\/shutterstock_1485719255.jpg?t=1786549389\"><\/div>\n<p><b>The Pharmacy Impact:<\/b> For Canadian pharmacy teams, vaccine cold-chain management is a daily operational pain point. Between purpose-built medical fridges, continuous glycol probe logging, and filling out paperwork whenever a summer storm trips a breaker, maintaining that strict +2&deg;C to +8&deg;C window takes real time and money. As noted in <i><a href=\"https:\/\/www.bmj.com\/content\/394\/bmj-2026-100517?utm_source=rxbriefly&amp;utm_medium=newsletter&amp;utm_campaign=ditching-the-vaccine-fridge\" target=\"_blank\" rel=\"noopener noreferrer nofollow\">The BMJ<\/a><\/i> and detailed in <a href=\"https:\/\/www.einpresswire.com\/article\/931875499\/the-lancet-s-eclinicalmedicine-publishes-phase-i-data-for-spvx02-a-fridge-free-td-vaccine-stable-for-24-months-at-30-c?utm_source=rxbriefly&amp;utm_medium=newsletter&amp;utm_campaign=ditching-the-vaccine-fridge\" target=\"_blank\" rel=\"noopener noreferrer nofollow\">EIN Presswire<\/a>, if larger trials confirm these Phase 1 results, thermostable formulations could transform pharmacy inventory by:<\/p>\n<ul>\n<li>\n<p><b>Zero Excursion Loss:<\/b> Power outages or door-ajar incidents wouldn&#8217;t mean quarantining or destroying thousands in stock.<\/p>\n<\/li>\n<li>\n<p><b>Easier Off-Site Clinics:<\/b> Travel health, workplace boosters, and mobile outreach in rural or northern communities wouldn&#8217;t require conditioned ice packs or transport loggers.<\/p>\n<\/li>\n<li>\n<p><b>Emergency Kit Ready:<\/b> Booster doses could sit on a standard shelf, in an emergency kit, or in an ambulance bay without needing a power plug.<\/p>\n<\/li>\n<\/ul>\n<p><span><b>But:<\/b><\/span><span> SPVX02 still has Phase 2 and 3 trials ahead before commercial approval, with development targeted through 2027. A Phase 1 trial in 60 adults shows promising safety and antibody responses, but broader testing is still needed to establish long-term real-world effectiveness and regulatory approval.<\/span><\/p>\n<p><b>Bottom Line:<\/b> While we&#8217;re still a few years away from tossing out the pharmacy fridge, proving that an aluminum-adjuvanted vaccine can survive room temperature sets a huge precedent. For pharmacists, it&#8217;s an exciting glimpse into a future where power outages no longer mean quarantining thousands of dollars in stock.<\/p>\n<\/div>\n<div>\n<h1><span>Hot Off The Press &#128478;&#65039;<\/span><\/h1>\n<\/div>\n<div>\n<div><img decoding=\"async\" alt=\"\" src=\"https:\/\/media.beehiiv.com\/cdn-cgi\/image\/fit=scale-down,format=auto,onerror=redirect,quality=80\/uploads\/asset\/file\/09d54950-9adf-43e9-a8ea-5ee37f7792ce\/shutterstock_1940986873.jpg?t=1786394623\"><\/div>\n<p><b>1:<\/b>&nbsp;&#128138;<b>&nbsp;<\/b>A vaccine just did what a century of shigella research couldn&#8217;t: <b>WRSs2, a live-attenuated oral vaccine<\/b>, posted 89% efficacy against shigellosis <a href=\"https:\/\/www.thelancet.com\/journals\/laninf\/article\/PIIS1473-3099(26)00224-0\/fulltext?utm_source=rxbriefly&amp;utm_medium=newsletter&amp;utm_campaign=ditching-the-vaccine-fridge\" target=\"_blank\" rel=\"noopener noreferrer nofollow\">in a phase 2 human challenge trial<\/a>, with only 3 of 34 vaccinated participants developing shigellosis versus 21 of 26 on placebo after deliberate S. sonnei exposure. The trial wasn&#8217;t entirely clean, with 6 participants experiencing grade 3 adverse events, and next up is testing in the kids who actually bear the brunt of the disease, since these results came from healthy US adults rather than the low-income settings where shigella does its worst damage,<\/p>\n<p><b>2:<\/b>&nbsp;&#129440; Don&#8217;t panic &mdash; <b>you haven&#8217;t time-travelled to 2020<\/b>. And yet COVID <a href=\"https:\/\/www.axios.com\/2026\/08\/10\/covid-pandemic-origin-fauci-lab-leak?utm_source=rxbriefly&amp;utm_medium=newsletter&amp;utm_campaign=ditching-the-vaccine-fridge\" target=\"_blank\" rel=\"noopener noreferrer nofollow\">is back in the news<\/a> to reveal some truth about its origins: we&#8217;ll probably never know it. A Senate panel voted to hold former US chief medical adviser Anthony Fauci in contempt of Congress after he pled the 5th <b>more than 100 times<\/b> during questioning about the pandemic response. Meanwhile, former US COVID-19 response coordinator Ashish Jha freely offered his take: &#8220;Here&#8217;s the truth: no one in America knows for sure,&#8221; and, &#8220;I think lab leak is much more likely.&#8221; But every theory remains unproven, and no first case has been identified. Don&#8217;t expect any satisfying answers to come out of this. Maybe just some nightmarish flashbacks of home-baked bread.<\/p>\n<p><b>3: <\/b>&#129514; An Ontario trial, <a href=\"https:\/\/www.cp24.com\/local\/toronto\/2026\/08\/09\/rapid-on-site-testing-at-ltc-homes-could-prevent-8000-er-visits-across-canada-every-year-trial-finds\/?utm_source=rxbriefly&amp;utm_medium=newsletter&amp;utm_campaign=ditching-the-vaccine-fridge\" target=\"_blank\" rel=\"noopener noreferrer nofollow\">PROMPT-LTC<\/a>, found that rapid on-site testing at long-term care homes could <b>prevent 8,000 ER visits<\/b> across Canada every year. 10 Ontario-area homes got on-site PCR testing for COVID, flu, and RSV with 35-minute results, versus 3 to 7 days at standard off-site labs, resulting in an <b>11% drop in ER transfers overall<\/b> and a 28% drop in transfers or deaths per 100 beds during peak RSV season. Outbreak sizes didn&#8217;t budge, but that&#8217;s likely because rapid-testing homes tested more than twice as often, catching milder cases the standard-testing homes were missing entirely.<\/p>\n<p><b>4:<\/b>&nbsp;&#129397;&nbsp;&#128166; Researchers may finally have something more satisfying than &ldquo;overactive sweat glands&rdquo; for some <b>hyperhidrosis patients<\/b>. <a href=\"https:\/\/www.science.org\/doi\/10.1126\/sciadv.aed3221?utm_source=rxbriefly&amp;utm_medium=newsletter&amp;utm_campaign=ditching-the-vaccine-fridge\" target=\"_blank\" rel=\"noopener noreferrer nofollow\">New data<\/a> links a subset of inherited cases to rare variants in SCN10A, a gene involved in the nerve signalling that controls sweating. They reproduced excessive sweating by putting one of the mutations into mice, then reducing it with sodium-channel inhibitors. It&#8217;s still early, but this knowledge could <b>lead to a targeted treatment<\/b>, rather than suppressing the symptoms with antiperspirants, Botox, and a duffel bag full of dry undershirts.<\/p>\n<\/div>\n<div>\n<h1><span>RxBriefly Picks <\/span>&#128138;<\/h1>\n<\/div>\n<div>\n<p>&#129438;&nbsp;<b>Visit: <\/b>Oscar, Dalhousie&#8217;s 1-in-50-million, half-blue, half-orange lobster, now on display at the <a href=\"https:\/\/www.cbc.ca\/news\/canada\/nova-scotia\/one-in-50-million-oscar-the-two-coloured-lobster-lands-in-n-s-aquarium-9.7294997?utm_source=rxbriefly&amp;utm_medium=newsletter&amp;utm_campaign=ditching-the-vaccine-fridge\" target=\"_blank\" rel=\"noopener noreferrer nofollow\">Beaty Centre for Marine Biodiversity in Halifax<\/a>. His two-toned colouring is genetic, so it grows back with every new shell. When was the last time you saw a genetic chimera up close?<\/p>\n<p>&#129514;&nbsp;<b>Track:<\/b>&nbsp;<a href=\"https:\/\/www.canada.ca\/en\/public-health\/news\/2026\/06\/canada-advances-new-medical-countermeasures-laboratory-facility-in-winnipeg.html?utm_source=rxbriefly&amp;utm_medium=newsletter&amp;utm_campaign=ditching-the-vaccine-fridge\" target=\"_blank\" rel=\"noopener noreferrer nofollow\">Ottawa&rsquo;s announcement<\/a> awarding a $10.2M design contract for a brand-new $267M Medical Countermeasures Laboratory in Winnipeg. Co-located with the National Microbiology Lab, it will focus on preclinical research into experimental vaccines and therapeutics for future pandemics.<\/p>\n<p>&#129516;&nbsp;<b>Note:<\/b> Health Canada&rsquo;s <a href=\"https:\/\/www.cbc.ca\/radio\/asithappens\/gay-bisexual-men-sperm-donations-9.7292647?utm_source=rxbriefly&amp;utm_medium=newsletter&amp;utm_campaign=ditching-the-vaccine-fridge\" target=\"_blank\" rel=\"noopener noreferrer nofollow\">milestone decision<\/a> to drop all remaining sexual behaviour screening questions for sperm donors. The decision eliminates the final systemic barriers that previously restricted gay and bisexual men from donating.<\/p>\n<p>&#128734;&nbsp;<b>Save:<\/b> on your pre-winter routine. Canadian Tire has <a href=\"https:\/\/www.canadiantire.ca\/en\/pdp\/michelin-x-ice-snow-winter-tire-for-passenger-cuv-clearance-0052090p.1082736.html?irclickid=zvv3BbRjgxyZWbNwP700gy5YUkr00xSsewps3U0&amp;irgwc=1&amp;afsrc=1&amp;utm_source=impact&amp;utm_medium=affiliate&amp;utm_term=842367&amp;id=impact_Skimbit%20Ltd._10078&amp;utm_campaign=Skimbit%20Ltd.&amp;utm_content=10078\" target=\"_blank\" rel=\"noopener noreferrer nofollow\">Michelin X-Ice Snow winter tires on clearance<\/a>. Getting ahead of snow season means shorter waits at the garage and extra cash left in your pocket<\/p>\n<p><b>&#127916; Watch: <\/b>how your brain turns moments into permanent physical structures. The video breaks down the cellular mechanics of <a href=\"https:\/\/www.youtube.com\/watch?v=PqtggjVAi8M&amp;utm_source=rxbriefly&amp;utm_medium=newsletter&amp;utm_campaign=ditching-the-vaccine-fridge\" target=\"_blank\" rel=\"noopener noreferrer nofollow\">memory formation<\/a> with gorgeous visuals that make neurobiology surprisingly soothing.<\/p>\n<\/div>\n<div>\n<h1><span>Relax <\/span>&#129513;<\/h1>\n<\/div>\n<div>\n<p><b>First clue<\/b>: Winter blues, for short<\/p>\n<div><a href=\"https:\/\/www.rxbriefcase.com\/fr\/rxbriefly-item\/rxbriefly-crossword-august-13th-2026\/?utm_source=rxbriefly&amp;utm_medium=newsletter&amp;utm_campaign=ditching-the-vaccine-fridge\" rel=\"noopener\" target=\"_blank\"><img decoding=\"async\" alt=\"\" src=\"https:\/\/media.beehiiv.com\/cdn-cgi\/image\/fit=scale-down,format=auto,onerror=redirect,quality=80\/uploads\/asset\/file\/ab948b99-1f55-4d24-b3f6-31408b3edbc8\/Screenshot_2026-08-12_at_9.26.08_AM.png?t=1786544801\"><\/a><\/p>\n<div><span><\/p>\n<p><span><i><b><a href=\"https:\/\/www.rxbriefcase.com\/fr\/rxbriefly-item\/rxbriefly-crossword-august-13th-2026\/?utm_source=rxbriefly&amp;utm_medium=newsletter&amp;utm_campaign=ditching-the-vaccine-fridge\" target=\"_blank\" rel=\"noopener noreferrer nofollow\">Give it a go &#10148;<\/a><\/b><\/i><\/span><\/p>\n<p><\/span><\/div>\n<\/div>\n<p><b>Need a rematch?<\/b> We&rsquo;ve got you covered. <b><a href=\"https:\/\/www.rxbriefcase.com\/fr\/rxbriefly\/?utm_source=rxbriefly&amp;utm_medium=newsletter&amp;utm_campaign=ditching-the-vaccine-fridge\" target=\"_blank\" rel=\"noopener noreferrer nofollow\">Check out our Crossword Archive<\/a><\/b> to find <i>every<\/i>&nbsp;<i>puzzle<\/i> we&rsquo;ve ever made, all in one place.<\/p>\n<p>Think you crushed it? Challenge your pharmacist friends to beat your time.<\/p>\n<\/div>\n<div>\n<h1><span>Meme Of The Week <\/span>&#128514;<\/h1>\n<\/div>\n<div>\n<div><img decoding=\"async\" alt=\"\" src=\"https:\/\/media.beehiiv.com\/cdn-cgi\/image\/fit=scale-down,format=auto,onerror=redirect,quality=80\/uploads\/asset\/file\/e28f5031-e736-4fe4-a66e-489f4f82c171\/pharmacy-memes-feat-oct-6.jpg?t=1786544717\"><\/div>\n<\/div>\n<div>\n<h1><span>Advertise with RXBriefly <\/span>&#128227;<\/h1>\n<\/div>\n<div>\n<p>Want to reach thousands of Canadian pharmacists every week? Email <a href=\"mailto:denis.bricov@mdbriefcase.com\" target=\"_blank\" rel=\"noopener noreferrer nofollow\">denis.bricov@mdbriefcase.com<\/a> to learn more.<\/p>\n<\/div>\n<div>\n<h1><span>Help Us Get Better <\/span>&#128591;<\/h1>\n<\/div>\n<div><\/div>\n<p>That&rsquo;s all for this issue.<\/p>\n<p>Cheers,<\/p>\n<p>The RxBriefly team.<\/p>\n<\/div>\n<div><\/p>\n<hr>\n<p><a target=\"_blank\" href=\"https:\/\/www.beehiiv.com\/?utm_campaign=8c15a60c-eeec-4a50-96a0-e9f740a4f50b&amp;utm_medium=post_rss&amp;utm_source=rxbriefly\">Powered by beehiiv<\/a><\/div>\n<\/div>","protected":false},"excerpt":{"rendered":"<p>Good morning dispensers of wisdom! Remember when getting sheep&#8217;s wool stuck to your sweater was just an annoying laundry mishap? Scientists have officially found a way to make it sound like high-tech medicine. A new study published this week found that extracting keratin from raw sheep&#8217;s wool can actually be used as a biological scaffold [&hellip;]<\/p>\n","protected":false},"author":20,"featured_media":89918,"menu_order":0,"template":"","meta":{"_acf_changed":false,"inline_featured_image":false,"footnotes":""},"categories":[1],"tags":[],"class_list":["post-89917","rxbriefly","type-rxbriefly","status-publish","has-post-thumbnail","hentry","category-uncategorized"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.9 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>\ud83d\udc8a Ditching the vaccine fridge? - RxBriefCase<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.rxbriefcase.com\/fr\/rxbriefly-item\/\ud83d\udc8a-ditching-the-vaccine-fridge\/\" \/>\n<meta property=\"og:locale\" content=\"fr_CA\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"\ud83d\udc8a Ditching the vaccine fridge? - RxBriefCase\" \/>\n<meta property=\"og:description\" content=\"Good morning dispensers of wisdom! Remember when getting sheep&#8217;s wool stuck to your sweater was just an annoying laundry mishap? Scientists have officially found a way to make it sound like high-tech medicine. A new study published this week found that extracting keratin from raw sheep&#8217;s wool can actually be used as a biological scaffold [&hellip;]\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.rxbriefcase.com\/fr\/rxbriefly-item\/\ud83d\udc8a-ditching-the-vaccine-fridge\/\" \/>\n<meta property=\"og:site_name\" content=\"RxBriefCase\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.rxbriefcase.com\/wp-content\/uploads\/2026\/08\/shutterstock_1955275207.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"1000\" \/>\n\t<meta property=\"og:image:height\" content=\"664\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data1\" content=\"9 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/www.rxbriefcase.com\\\/rxbriefly-item\\\/%f0%9f%92%8a-ditching-the-vaccine-fridge\\\/\",\"url\":\"https:\\\/\\\/www.rxbriefcase.com\\\/rxbriefly-item\\\/%f0%9f%92%8a-ditching-the-vaccine-fridge\\\/\",\"name\":\"\ud83d\udc8a Ditching the vaccine fridge? - RxBriefCase\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/www.rxbriefcase.com\\\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\\\/\\\/www.rxbriefcase.com\\\/rxbriefly-item\\\/%f0%9f%92%8a-ditching-the-vaccine-fridge\\\/#primaryimage\"},\"image\":{\"@id\":\"https:\\\/\\\/www.rxbriefcase.com\\\/rxbriefly-item\\\/%f0%9f%92%8a-ditching-the-vaccine-fridge\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/www.rxbriefcase.com\\\/wp-content\\\/uploads\\\/2026\\\/08\\\/shutterstock_1955275207.jpg\",\"datePublished\":\"2026-08-13T15:00:00+00:00\",\"breadcrumb\":{\"@id\":\"https:\\\/\\\/www.rxbriefcase.com\\\/rxbriefly-item\\\/%f0%9f%92%8a-ditching-the-vaccine-fridge\\\/#breadcrumb\"},\"inLanguage\":\"fr-CA\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\\\/\\\/www.rxbriefcase.com\\\/rxbriefly-item\\\/%f0%9f%92%8a-ditching-the-vaccine-fridge\\\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"fr-CA\",\"@id\":\"https:\\\/\\\/www.rxbriefcase.com\\\/rxbriefly-item\\\/%f0%9f%92%8a-ditching-the-vaccine-fridge\\\/#primaryimage\",\"url\":\"https:\\\/\\\/www.rxbriefcase.com\\\/wp-content\\\/uploads\\\/2026\\\/08\\\/shutterstock_1955275207.jpg\",\"contentUrl\":\"https:\\\/\\\/www.rxbriefcase.com\\\/wp-content\\\/uploads\\\/2026\\\/08\\\/shutterstock_1955275207.jpg\",\"width\":1000,\"height\":664},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\\\/\\\/www.rxbriefcase.com\\\/rxbriefly-item\\\/%f0%9f%92%8a-ditching-the-vaccine-fridge\\\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\\\/\\\/www.rxbriefcase.com\\\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"RxBriefly\",\"item\":\"https:\\\/\\\/www.rxbriefcase.com\\\/fr\\\/rxbriefly-item\\\/\"},{\"@type\":\"ListItem\",\"position\":3,\"name\":\"\ud83d\udc8a Ditching the vaccine fridge?\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\\\/\\\/www.rxbriefcase.com\\\/#website\",\"url\":\"https:\\\/\\\/www.rxbriefcase.com\\\/\",\"name\":\"RxBriefCase\",\"description\":\"\",\"publisher\":{\"@id\":\"https:\\\/\\\/www.rxbriefcase.com\\\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\\\/\\\/www.rxbriefcase.com\\\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"fr-CA\"},{\"@type\":\"Organization\",\"@id\":\"https:\\\/\\\/www.rxbriefcase.com\\\/#organization\",\"name\":\"RxBriefCase\",\"url\":\"https:\\\/\\\/www.rxbriefcase.com\\\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"fr-CA\",\"@id\":\"https:\\\/\\\/www.rxbriefcase.com\\\/#\\\/schema\\\/logo\\\/image\\\/\",\"url\":\"https:\\\/\\\/www.rxbriefcase.com\\\/wp-content\\\/uploads\\\/2024\\\/07\\\/logo.webp\",\"contentUrl\":\"https:\\\/\\\/www.rxbriefcase.com\\\/wp-content\\\/uploads\\\/2024\\\/07\\\/logo.webp\",\"width\":190,\"height\":36,\"caption\":\"RxBriefCase\"},\"image\":{\"@id\":\"https:\\\/\\\/www.rxbriefcase.com\\\/#\\\/schema\\\/logo\\\/image\\\/\"}}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"\ud83d\udc8a Ditching the vaccine fridge? - RxBriefCase","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/www.rxbriefcase.com\/fr\/rxbriefly-item\/\ud83d\udc8a-ditching-the-vaccine-fridge\/","og_locale":"fr_CA","og_type":"article","og_title":"\ud83d\udc8a Ditching the vaccine fridge? - RxBriefCase","og_description":"Good morning dispensers of wisdom! 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